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What is the effect of protein C and S on pergnancy??


Question: existing higher amount than normal , and relative effects on pregnancy? abbortion ? solutions?
Answers: Proteins C and S are normal physiological components of the protein complexes that regulate blood clotting, in particular they are endogenous anticoagulants.

Disorders of these proteins are usually hereditary defects and needless to say can lead to abnormalities in blood clotting.

Activated protein C deficiency is a problematic disorder leading to a prothrombotic tendency (ie you are more prone to clots: DVT or PE) and needs to be brought to the attention of your obstetrician.

Excess levels theoreticall will predispose to bleeding disorders, important of course in regard to placental separation and potentially a risk to the mother during child birth, or the baby if it leads to placental abruption.

I would suggest if you have been given this diagnosis you discuss the consequences with your obstetrician as it need not be a catastrophe for mother or child so long as your doctors are aware of its presence throughout your care.


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